%0 Journal Article
%T 1,5-Diazacyclohenicosane, a New Cytotoxic Metabolite from the Marine Sponge Mycale sp.
%A Laura Coello
%A Mar¨ªa Jes¨²s Mart¨ªn
%A Fernando Reyes
%J Marine Drugs
%D 2009
%I MDPI AG
%R 10.3390/md7030445
%X A new cyclic diamine, 1,5-diazacyclohenicosane (1), was isolated from samples of the marine sponge Mycale sp. collected at Lamu Island (Kenya). Its structure was determined by a combination of spectroscopic techniques, including (+)-HRESIMS and 1D and 2D NMR spectroscopy. The compound displayed cytotoxicity at the ¦ÌM level against three human tumor cell lines.
%K marine sponges
%K alkaloids
%K cytotoxicity
%K Mycale sp.
%U http://www.mdpi.com/1660-3397/7/3/445