%0 Journal Article
%T ACID SENSITIVE MICELLAR AGGREGATES BASED ON AMPHIPHILIC BLOCK COPOLYMERS WITH PENDANT CYCLIC ORTHOESTER<br>含环状原酸酯侧基的两亲性嵌段共聚物及其酸敏感胶束状聚集体
%A HUANG Xiao-nan
%A DU Fu-sheng
%A YANG Jun
%A LI Zi-chen
%A <br>黄潇楠
%A 杜福胜
%A 杨俊
%A 李子臣
%J 高分子学报
%D 2009
%I 
%X Acid-sensitive polymeric micelles have great potential as carriers for target drug delivery systems.In this work,a methacrylate monomer with cyclic orthoester group,(2-ethoxy-5-methyl-1,3-dioxan-5-yl)methyl methacrylate(EDMM),was synthesized.Two acid-sensitive amphiphilic block copolymers,PEO-b-PEDMM_ 17 and PEO-b-PEDMM_ 34,were prepared by the atom transfer radical polymerization of EDMM using a PEO macroinitiator(molecular weight ca.2000 Da).The compositions and molecular weights of the two block copolyme...
%K Orthoester
%K PEO
%K Block copolymer
%K Acid-sensitive
%K Micellar aggregate<br>原酸酯
%K 聚乙二醇
%K 嵌段共聚物
%K 酸敏感
%K 胶束状聚集体
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=6E709DC38FA1D09A4B578DD0906875B5B44D4D294832BB8E&cid=6579068328FE643F&jid=15971983683C7643EE80F1CE621DEB60&aid=0B31429F44E6CB58BAEC0996B7279AE3&yid=DE12191FBD62783C&iid=CA4FD0336C81A37A&sid=7E8E8B150580E4AB&eid=08805F9252973BA4&journal_id=1000-3304&journal_name=高分子学报&referenced_num=0&reference_num=16