%0 Journal Article %T The Chemistry and Pharmacology of Anatoxin-a and Related Homotropanes with respect to Nicotinic Acetylcholine Receptors %A Susan Wonnacott %A Timothy Gallagher %J Marine Drugs %D 2006 %I MDPI AG %R 10.3390/md403228 %X This chapter covers the chemistry and nicotinic pharmacology of naturally occurring homotropane alkaloids, with an emphasis of anatoxin-a. In addition to anatoxin-a, homoanatoxin and pinnamine, as well as the major classes of synthetic derivatives of anatoxin-a including UB-165, are discussed. %K anatoxin-a %K homoanatoxin %K UB165 %K pinnamine %K homotropane %K nicotinic acetylcholine receptor %K pharmacophore %U http://www.mdpi.com/1660-3397/4/3/228