%0 Journal Article
%T Polycitorols A and B, New Tricyclic Alkaloids from an Ascidian
%A Hamad H. Issa
%A Junichi Tanaka
%A Rachmaniar Rachmat
%A Andi Setiawan
%A Agus Trianto
%A Tatsuo Higa
%J Marine Drugs
%D 2005
%I MDPI AG
%R 10.3390/md303078
%X Two new tricyclic alkaloids, polycitorols A (1) and B (2) have been isolated along with the known lepadiformine (3) from a marine ascidian of the family Polycitoridae. The structures of the new compounds were elucidated by analysis of NMR data and comparison with those of 3 and other related compounds [1-5]. Compounds 1 and 2 are closely related to cylindricines A and B, lacking C-4 oxygenation found in cylindricines and having a butyl instead of a hexyl appendage. NOE experiments on compounds 1 and 2 suggested the A/B ring fusion to be cis.
%K polycitorols
%K Polycitoridae
%K tricyclic alkaloids
%K ascidian
%K polycyclic alkaloids
%U http://www.mdpi.com/1660-3397/3/3/78