%0 Journal Article %T Secomycalolide A: A New Proteasome Inhibitor Isolated from a Marine Sponge of the Genus Mycale %A Sachiko Tsukamoto %A Keiichirou Koimaru %A Tomihisa Ohta %J Marine Drugs %D 2005 %I MDPI AG %R 10.3390/md302029 %X A new oxazole-containing proteasome inhibitor, secomycalolide A, together with known mycalolide A and 30-hydroxymycalolide A, was isolated from a marine sponge of the genus Mycale. They showed proteasome inhibitory activities with IC50 values of 11-45 ¦Ìg/mL. %K proteasome inhibitor %K secomycalolide A %K mycalolide A %K marine sponge %K Mycale %U http://www.mdpi.com/1660-3397/3/2/29