%0 Journal Article
%T Visual Study on the Formation of Naproxen Particles with Different Morphologies<br>多形貌萘普生药物晶体生长的可视化研究
%A JIN Kang-kang
%A CHENG Jing
%A WEN Li-xiong
%A CHEN Jian-feng
%A <br>金康康
%A 程靖
%A 文利雄
%A 陈建峰
%J 过程工程学报
%D 2007
%I 
%X A new technology was proposed to visually study the crystallization morphologies of naproxen particles synthesized by reaction-precipitation. The effects of surfactant type and concentration, naproxen concentration and reacting temperature on the morphology and size of the synthesized naproxen particles were investigated, and the growth mechanism of particles was discussed briefly. It was found that needle-like, spherical, butterfly-like and rod-like crystals of naproxen particles could be obtained respectively in the presence of Tween-80, PVP, Karomic-90 or CMC. Naproxen concentration, surfactant concentration and reacting temperature could also influence the particle size significantly.
%K naproxen
%K surfactant
%K crystallization
%K visualization<br>萘普生
%K 表面活性剂
%K 晶体生长
%K 可视化
%K 多形
%K 生药物
%K 晶体生长
%K 可视化研究
%K Different
%K Particles
%K Naproxen
%K Formation
%K Study
%K 表面活性剂浓度
%K 蝴蝶
%K 球状
%K 针状
%K 可分
%K 作用
%K 结果
%K 生长机理
%K 颗粒形貌
%K 影响
%K 尺寸
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=5B3AB970F71A803DEACDC0559115BFCF0A068CD97DD29835&cid=3FCF8B1A330466D5&jid=B9EE12934D19905403D996AE65CEEEED&aid=BDAB0BFD4B506E5A19B8A94905FCA27F&yid=A732AF04DDA03BB3&vid=DF92D298D3FF1E6E&iid=B31275AF3241DB2D&sid=0522AC581E488FBF&eid=9E9FFC2CDB44A291&journal_id=1009-606X&journal_name=过程工程学报&referenced_num=0&reference_num=14