%0 Journal Article
%T Strategies for Expression of Soluble Heterologous Proteins in Escherichia coli<br>外源蛋白在大肠杆菌中的可溶性表达策略
%A ZHU Hong-yu
%A LI Qiang
%A <br>朱红裕
%A 李强
%J 过程工程学报
%D 2006
%I 
%X Escherichia coli has long been the primary expression system for the synthesis of heterologous proteins, but its utility is limited because many heterologous proteins are either prone to be degraded by the cellular proteases or to accumulate in insoluble form, typically as inclusion bodies. This paper reviews recent advances in the strategies for expression soluble heterologous proteins in Escherichia coli so as to improve the recovery yield of heterologous gene products in a biologically active form.
%K heterologous protein
%K soluble expression
%K Escherichia coli<br>外源蛋白
%K 可溶性表达
%K 大肠杆菌
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=5B3AB970F71A803DEACDC0559115BFCF0A068CD97DD29835&cid=3FCF8B1A330466D5&jid=B9EE12934D19905403D996AE65CEEEED&aid=FD1B5832A0DA7EA7&yid=37904DC365DD7266&vid=B31275AF3241DB2D&iid=CA4FD0336C81A37A&sid=2DBBF45CC176713E&eid=7CE3F1F20DE6B307&journal_id=1009-606X&journal_name=过程工程学报&referenced_num=12&reference_num=66