%0 Journal Article
%T Development of Ti-Coated Ferromagnetic Needle, Adaptable for Ablation Cancer Therapy by High-Frequency Induction Heating
%A Takashi Naohara
%A Hiromichi Aono
%A Tsunehiro Maehara
%A Hideyuki Hirazawa
%A Shinya Matsutomo
%A Yuji Watanabe
%J Journal of Functional Biomaterials
%D 2012
%I MDPI AG
%R 10.3390/jfb3010163
%X To develop a novel ablation therapy for human solid cancer, the heating properties of a ferromagnetic carbon steel rod and a prototype Ti-coated needle using this carbon steel rod, were investigated in several high-frequency outputs at 300 kHz. In the former, the heating property was drastically different among the three inclination angles (¦È = 0¡ã, 45¡ã and 90¡ã) relative to the magnetic flux direction as a result of the shape magnetic anisotropy. However, the effect of the inclination angles was completely eliminated in the latter. It is considered that the complete non-oriented heating property relative to the magnetic flux direction allows the precise control of the ablation temperature during minimally invasive thermotherapy without a lead-wire connected to a fiber-optic thermometer. This newly designed Ti-coated device will be suitable for clinical use combined with its superior biocompatibility for ablation treatments using high-frequency induction heating.
%K cancer therapy
%K ablation treatment
%K high-frequency induction heating
%K AC magnetic field
%K shape magnetic anisotropy
%K magnetic flux direction
%K biocompatibility
%U http://www.mdpi.com/2079-4983/3/1/163