%0 Journal Article
%T Preliminary Evaluation of the Thromboresistance of ZnO Nanoparticles<br>ZnO纳米材料抗凝血性能的初步评价
%A LI Chao
%A HU Guo-dong
%A HE Yan-hua
%A <br>李潮
%A 胡国栋
%A 何艳花
%J 过程工程学报
%D 2003
%I 
%X Evaluation of antithrombogenicity of ZnO nanoparticles was carried out based on the measurements of in vitro kinetic clotting time. The average size of the ZnO nanoparticles was 10~30 nm. The research was divided into the control group (1 ml of whole blood), the non-nanoparticles group (1 ml of whole blood, including 0.4 ml of the stirred plasma), the ZnO group (1 ml of whole blood, including 0.4 ml of the stirred plasma and 1 mg of ZnO nanoparticles) and the Fe group (1 ml of whole blood, including 0.4 ml of the stirred plasma and 1 mg of Fe nanoparticles). Measurements of clotting time of every group were carried out at 5, 15, 30 and 45 min. The calculated results revealed that the thromboresistant radio was remained at 70% in 45 min in the ZnO nanoparticles group, while the radio dropped to 30% in 15 min in the control group, the non-nanoparticles group and the Fe group. The results predict that the ZnO nanoparticles have excellent thromboresistant property.
%K thromboresistance
%K ZnO
%K nanomaterials<br>抗凝血
%K ZnO
%K 纳米材料
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=5B3AB970F71A803DEACDC0559115BFCF0A068CD97DD29835&cid=3FCF8B1A330466D5&jid=B9EE12934D19905403D996AE65CEEEED&aid=A0F6AB19E0E40C51&yid=D43C4A19B2EE3C0A&vid=38B194292C032A66&iid=CA4FD0336C81A37A&sid=339D79302DF62549&eid=933658645952ED9F&journal_id=1009-606X&journal_name=过程工程学报&referenced_num=3&reference_num=5