%0 Journal Article
%T Improvement of the Fermentation Productivity of a New Antibiotic AGPM by Orthogonal Design Experiment<br>抗生素AGPM摇瓶发酵条件的正交实验
%A SHI Bing-xing
%A ZHAO Hong
%A LIU Xi-peng
%A YUAN Ying-jin
%A HU Zong-ding
%A <br>石炳兴
%A 赵红
%A 刘喜朋
%A 王英进
%A 胡宗定
%J 过程工程学报
%D 2001
%I 
%X The effects of medium composition on the activity of a new antibiotic APGM was studied by orthogonal design experiment. It seems that nitrogen source presented the most significant effect on the production of AGPM and that higher ratio of carbon to nitrogen was beneficial. It was concluded that the fermentation activity was increased by 18.9 times to 1562.2 u/ml under the optimal conditions as the medium was composed of glucose 5 g/L,corn starch 40 g/L, soybean meal 16 g/L, corn steep liqour 2 ml, K2HPO4 1.0 g/L, MgSO4?H2O 0.5 g/L, NaCl 0.5 g/L and amylase 0.05 g/L.
%K antibiotic
%K medium
%K Streptomyces
%K orthogonal design<br>抗生素
%K 培养基
%K 链霉菌
%K 正交实验
%K 发酵
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=5B3AB970F71A803DEACDC0559115BFCF0A068CD97DD29835&cid=3FCF8B1A330466D5&jid=B9EE12934D19905403D996AE65CEEEED&aid=F12F824B5942FCEF&yid=14E7EF987E4155E6&vid=CA4FD0336C81A37A&iid=E158A972A605785F&sid=D98387EFB283C5E0&eid=68FDAD96FCC0AB1B&journal_id=1009-606X&journal_name=过程工程学报&referenced_num=12&reference_num=4