%0 Journal Article
%T Production of Protocatechuic Acid in Bacillus Thuringiensis ATCC33679
%A Kimtrele M. Williams
%A William E. Martin
%A Justin Smith
%A Baraka S. Williams
%A Bianca L. Garner
%J International Journal of Molecular Sciences
%D 2012
%I MDPI AG
%R 10.3390/ijms13033765
%X Protocatechuic acid, or 3,4-dihydroxybenzoic acid, is produced by both soil and marine bacteria in the free form and as the iron binding component of the siderophore petrobactin. The soil bacterium, Bacillus thuringiensis kurstaki ATCC 33679, contains the asb operon, but does not produce petrobactin. Iron restriction resulted in diminished B. thuringiensis kurstaki ATCC 33679 growth and the production of catechol(s). The gene product responsible for protocatechuic acid ( asbF) and its receptor ( fatB) were expressed during stationary phase growth. Gene expression varied with growth temperature, with optimum levels occurring well below the Bacillus anthracis virulence temperature of 37 ˇăC. Regulation of protocatechuic acid suggests a possible role for this compound during soil growth cycles.
%K catechol
%K Bacillus
%K protocatechuic acid
%U http://www.mdpi.com/1422-0067/13/3/3765