%0 Journal Article
%T Sol-Gel-Derived Hydroxyapatite-Carbon Nanotube/Titania Coatings on Titanium Substrates
%A Xiaoli Ji
%A Weiwei Lou
%A Qi Wang
%A Jianfeng Ma
%A Haihong Xu
%A Qing Bai
%A Chuantong Liu
%A Jinsong Liu
%J International Journal of Molecular Sciences
%D 2012
%I MDPI AG
%R 10.3390/ijms13045242
%X In this paper, hydroxyapatite-carbon nanotube/titania (HA-CNT/TiO 2) double layer coatings were successfully developed on titanium (Ti) substrates intended for biomedical applications. A TiO 2 coating was firstly developed by anodization to improve bonding between HA and Ti, and then the layer of HA and CNTs was coated on the surface by the sol-gel process to improve the biocompatibility and mechanical properties of Ti. The surfaces of double layer coatings were uniform and crack-free with a thickness of about 7 ¦Ìm. The bonding strength of the HA-CNT/TiO 2 coating was higher than that of the pure HA and HA-CNT coatings. Additionally, in vitro cell experiments showed that CNTs promoted the adhesion of preosteoblasts on the HA-CNT/TiO 2 double layer coatings. These unique surfaces combined with the osteoconductive properties of HA exhibited the excellent mechanical properties of CNTs. Therefore, the developed HA-CNT/TiO 2 coatings on Ti substrates might be a promising material for bone replacement.
%K hydroxyapatite
%K carbon nanotubes
%K titania
%K anodization
%K sol-gel process
%U http://www.mdpi.com/1422-0067/13/4/5242