%0 Journal Article
%T Antimicrobial Peptides Purified from Penus chinensis<br>中国对虾PC-Ⅲ系列抗菌肽的分离纯化及活性
%A AN Xian-hui
%A LV Yi
%A LI Wei-guo
%A LIANG Jian-guo
%A XU Chun-hua
%A ZHANG Chong-xing
%A DONG Jing
%A LAI Ren
%A <br>安贤惠
%A 吕毅
%A 李卫国
%A 梁建国
%A 徐春花
%A 张崇星
%A 董靖
%A 赖仞
%J 动物学研究
%D 2005
%I Chinese Academy of Sciences
%X Two antimicrobial peptides were purified from Penus chinensis by Sephadex G-50 gel filtration and reverse phase high performance liquid chromatography. The molecular weights were 1 071 and 1 311 Da respectively, determined by matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry. They inhibited the growth of Gram-positive and Gram-negative bacteria. The antimicrobial peptides strengthened the contractile response of isolated mice ileum. Serine proteases did not affect hydrolytic activities in our current experiments. These antimicrobial peptides play an important role in preventing microbial infection in P. chinensis.
%K Penus chinensis
%K Antimicrobial peptide
%K Separation and purification<br>中国对虾
%K 抗菌肽
%K 分离纯化
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=7C502F1A6798ACE1B8C57E291C48C7F1&aid=C9B6A54969381945&yid=2DD7160C83D0ACED&vid=96C778EE049EE47D&iid=E158A972A605785F&sid=FED44C0135DC1D9C&eid=BFB86B6ED3A99B9D&journal_id=0254-5853&journal_name=动物学研究&referenced_num=3&reference_num=20