%0 Journal Article
%T Characterization of CaPKR-like Expression in Tissues from Crucian and Grass Carp<br>CaPKR-like在鲫鱼与草鱼组织中的表达特性分析
%A PENG Wu
%A TANG Ya-nan
%A HU Cheng-yu
%A <br>彭悟
%A 汤雅男
%A 胡成钰
%J 动物学研究
%D 2007
%I Chinese Academy of Sciences
%X Double-stranded RNA activated protein kinase (PKR) is an important antiviral protein induced by interferon (IFN). PKR was discovered as the enzyme responsible for inhibition of protein synthesis. CaPKR-like is the first fish PKR-like gene isolated from crucian carp. In the present study, the expression of CaPKR-like in the tissues of crucian and grass carp were analyzed by Western blots. In both species, CaPKR-like had a very low level of constitutive expression in un-stimulated tissues, but was up-regulated in all tissues tested in animals stimulated with Poly I:C for seven days. The expression analysis revealed the same characterization of CaPKR-like as mammalian PKR genes.
%K PKR
%K CaPKR-like
%K Expression
%K Crucian carp
%K Grass carp<br>表达
%K 鲫鱼
%K 草鱼
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=7C502F1A6798ACE1B8C57E291C48C7F1&aid=0CD1C03DC0E652641FDC48F38F6AFBBE&yid=A732AF04DDA03BB3&vid=D3E34374A0D77D7F&iid=94C357A881DFC066&sid=BC88D6B0750E09D1&eid=8F2250DA83AF77B8&journal_id=0254-5853&journal_name=动物学研究&referenced_num=0&reference_num=19