%0 Journal Article
%T Screen Printing Bio-chip Sensor for Cholesterol Detection Based on Molecular Imprinting Self-assembled Film<br>基于分子印迹聚合膜的胆固醇丝网印刷生物传感芯片
%A Xue Qian-nan
%A Bian Chao
%A Ren Zhen-xing
%A Sun Ji-zhou
%A Bian He-ming
%A Han Jing-hong
%A Xia Shan-hong
%A <br>薛茜男
%A 边超
%A 任振兴
%A 孙楫舟
%A 卞贺明
%A 韩泾鸿
%A 夏善红
%J 电子与信息学报
%D 2010
%I 
%X An electrochemical bionic sensor for cholesterol detection is developed with molecular imprinting self-assembled film deposited on the screen printed gold electrode. The surface topography of planar bare gold electrode and thick film bare gold electrode are compared with Scanning Electron Microscope (SEM). The electrochemical characteristics of the electrode during modification are studied with cyclic voltammetry technique. The results show that thick film electrode by screen printing technology is suited to the modification of molecular imprinting self-assembled film, and exhibits obvious amplification at nano level. The response of the sensor to the concentration of cholesterol is detected with chronoamperometric measurements. Cholesterol between 0 and 700 nM are detected with this sensor. The linearity range is from 50 nM to 700 nM with the sensitivity of -4.94 μA/lg(nM)] and linearly dependent coefficient of 0.994. And this cholesterol sensor has high accuracy, which reaches 99.56%.
%K Electrochemical sensor
%K Molecular imprinting
%K SAM
%K Cholesterol
%K Screen printing<br>电化学传感芯片
%K 分子印迹
%K 自组装单层膜
%K 胆固醇
%K 丝网印刷
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=5B3AB970F71A803DEACDC0559115BFCF0A068CD97DD29835&cid=1319827C0C74AAE8D654BEA21B7F54D3&jid=EFC0377B03BD8D0EF4BBB548AC5F739A&aid=3776C19EB25938E2B7FEAE4CEF62ED1A&yid=140ECF96957D60B2&vid=9971A5E270697F23&iid=708DD6B15D2464E8&sid=011F1533B0A7A0B2&eid=D87173A90452242E&journal_id=1009-5896&journal_name=电子与信息学报&referenced_num=0&reference_num=17