%0 Journal Article
%T Studies on Unsterile Fermentation Process of Honggumycin<br>红谷霉素生料发酵工艺的研究
%A XIONG Zhi-qiang
%A TU Xiao-rong
%A TU Guo-quan
%A <br>熊智强
%A 涂晓嵘
%A 涂国全
%J 中国生物工程杂志
%D 2008
%I 
%X Honggumycin, which showed a significant antibacterial activity, was a bioactive compound obtained by the fermentation broth of Streptomyces 702. Under the shaking-flask culture, unsterile fermentation process of honggumycin produced by Streptomyces 702 were studied by single-factor experiment design. The optimum unsterile shaking-flask cultivation condition consisted of: 7.5% of inoculation size (v/v), 1.5mL of antimicrobial agent addition. Under the optimal conditions, honggumycin yield of unsterile fermentation was up to 1.46g/L, which was increased by 25.7% than that of sterile fermentation. The result showed that fermentation for Streptomyces 702 under non-sterile conditions was an potentially efficient fermentation mode, which not only saved fermentation cost, but also increased fermentation productivity.
%K Streptomyces 702
%K honggumycin
%K unsterile fermentation
%K process<br>链霉菌702
%K 红谷霉素
%K 生料发酵
%K 发酵工艺
%K 研究
%K Fermentation
%K Process
%K 成本
%K 节约
%K 发酵方法
%K 结果
%K 实验探索
%K 产量提高
%K 灭菌
%K 摇瓶发酵
%K 生料发酵
%K 在此条件下
%K 抗菌剂
%K 添加
%K 接种量
%K 种子
%K 发酵条件
%K 筛选
%K 单因素
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=951380788B355DEA7D75520FA3B199C9&aid=D9C7BB4B354229FF100141CDCEC58A56&yid=67289AFF6305E306&vid=D3E34374A0D77D7F&iid=CA4FD0336C81A37A&sid=228A710F49B6CE58&eid=9C65ADEB5990B252&journal_id=1671-8135&journal_name=中国生物工程杂志&referenced_num=0&reference_num=12