%0 Journal Article
%T Progress on the study of sex-specific membrane proteins<br>哺乳动物精子性别特异膜蛋白的研究进展
%A WANG Dong
%A WANG Zhen-ling
%A CHENG Jin-hua
%A ZHU Hua-bin
%A HAO Hai-sheng
%A LIU Yong-hua
%A <br>王栋
%A 王振铃
%A 程金华
%A 朱化彬
%A 郝海生
%A 刘永华
%J 中国生物工程杂志
%D 2006
%I 
%X The expression of specific genes in sex chromosomes is the basis of sex-specific membrane protein in mammalian spermatozoa. The gene expression products are shared among spermatozoa through intercellular bridges, however, the phenomena of male transmission-ratio distortion and sex ratio distortion proved that differential proteins exist between X and Y spermatozoa. In addition, the existence of sex-specific proteins was confirmed by the separation experiment of X/Y chromosome bearing spermatozoa and the detection result of sex specific proteins. At the same time, it was also confirmed that the difference of the sex-specific protein is weak . The advance of separation techniques as well as the integration and optimization among these techniques has made it possible to separate sex-specific membrane proteins in mammalian spermatozoa.
%K Differential membrane protein Spermatozoa Gene expression<br>差异膜蛋白
%K 精子
%K 基因表达
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=951380788B355DEA7D75520FA3B199C9&aid=44E1882C6585C4BA&yid=37904DC365DD7266&vid=96C778EE049EE47D&iid=CA4FD0336C81A37A&sid=8BD23BD67BF01A5C&eid=68D88C2FCF9C3098&journal_id=1671-8135&journal_name=中国生物工程杂志&referenced_num=0&reference_num=22