%0 Journal Article
%T Novel progress in separation and purification technology of nattokinase<br>纳豆激酶集成化分离技术
%A GOU Jin-xia
%A GAO Dong
%A <br>苟金霞
%A 高栋
%J 中国生物工程杂志
%D 2008
%I 
%X The progress in separation and purification technology of nattokinase is reviewed. Based on the analyze of normal purification technology, the novel technologies about the integration of bioseparation processes are introduced, such as aqueous two-phase partitioning integrated with affinity ligand, expanded bed adsorption, and mixed-mode adsorption technology. In general, integration of bioseparation processes provides a good way to improve and optimize the whole separation process of nattokinase and other proteins.
%K nattokinase
%K purification
%K integration
%K salt-independent adsorption<br>纳豆激酶
%K 分离纯化
%K 集成化
%K 耐盐吸附
%K 纳豆激酶
%K 集成化
%K 分离技术
%K Nattokinase
%K Technology
%K Separation
%K and
%K Purification
%K Progress
%K 前景
%K 活性蛋白
%K 生产
%K 分离方法
%K 混合模式
%K 耐盐性
%K 吸附技术
%K 扩张床
%K 分配技术
%K 双水相
%K 优势
%K 应用
%K 重点
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=951380788B355DEA7D75520FA3B199C9&aid=65493F8FBDFED2C93AB981542234A539&yid=67289AFF6305E306&vid=D3E34374A0D77D7F&iid=CA4FD0336C81A37A&sid=EFD65B51496FB200&eid=AE09EACBCD1B2A13&journal_id=1671-8135&journal_name=中国生物工程杂志&referenced_num=0&reference_num=18