%0 Journal Article
%T Mechanism of Signal Transduction in Bacterial Quorum Sensing System and Its Role in Antibiotics Production<br>细菌群体感应的信号转导机制及其对抗生素生产的影响
%A WANG Jian-Hua
%A <br>王建华
%A 权春善
%A 李新
%J 中国生物工程杂志
%D 2008
%I 
%X Abstract: Quorum sensing is a cell-density-dependent regulatory mechanism.A lot of bacteria have the ability to secrete one or more kinds of signal molecules.They utilize the signal molecules to feel the bacteria density and regulate a series of target genes expression,but the effect of signal molecules on the production of antibiotics is the investigation focus.This article reviews the new advancement of quorum sensing mechanism,the effect of it on the antibiotics production,and pay more attention to Burkholderia cepacia.
%K Quorum sensing
%K Signal molecules
%K Target genes
%K Burkholderia cepacia
%K Quorum sensing
%K Signal molecules<br>群体感应
%K 信号分子
%K 靶基因
%K 洋葱伯克霍尔德菌
%K 细菌群体感应
%K 信号转导机制
%K 抗生素
%K 生产
%K 影响
%K Production
%K Antibiotics
%K Role
%K Quorum
%K Sensing
%K System
%K Bacterial
%K Signal
%K Transduction
%K Burkholderia
%K 洋葱伯克霍尔德菌
%K 研究进展
%K 调节
%K 靶基因
%K 表达
%K 调控机制
%K 密度
%K 感知
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=951380788B355DEA7D75520FA3B199C9&aid=E335F06D5024CB7AFC82A7BB9470D044&yid=67289AFF6305E306&vid=D3E34374A0D77D7F&iid=E158A972A605785F&sid=117F81797AB182FC&eid=08805F9252973BA4&journal_id=1671-8135&journal_name=中国生物工程杂志&referenced_num=1&reference_num=22