%0 Journal Article
%T Numerical Simulations of Calcium Ions Spiral Wave in Single Cardiac Myocyte<br>
%A BAI Yong-Qiang
%A ZHU Xing
%A <br>
%J 中国物理快报
%D 2010
%I 
%X The calcium ions (Ca2+) spark is an elementary Ca2+ release event in cardiac myocytes. It is believed to buildup cell-wide Ca2+ signals, such as Ca2+ transient and Ca2+ wave, through a Ca2+-induced Ca2+ release (CICR) mechanism. Here the excitability of the Ca2+ wave in a single cardiac myocyte is simulated by employing the fire-diffuse-fire model. By modulating the dynamic parameters of Ca2+ release and re-uptake channels, we find three Ca2+ signaling states in a single cardiac myocyte: no wave, plane wave, and spiral wave. The period of a spiral wave is variable in the different regimes. This study indicates that the spiral wave or the excitability of the system can be controlled through micro-modulation in a living excitable medium.
%K 82
%K 39
%K Rt
%K 87
%K 16
%K Xa
%K 89
%K 75
%K Kd<br>
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=6E709DC38FA1D09A4B578DD0906875B5B44D4D294832BB8E&cid=47EA7CFDDEBB28E0&jid=E27DA92E19FE279A273627875A70D74D&aid=18B888B58943A412FCC3825407226DFF&yid=140ECF96957D60B2&vid=DB817633AA4F79B9&iid=E158A972A605785F&journal_id=0256-307X&journal_name=中国物理快报&referenced_num=0&reference_num=0