%0 Journal Article
%T Metabolic Profiles in Human Hepatic Tumors Analyzed by In Vitro High-resolution Magic-angle-spinning 1H NMR Spectroscopy<br>肝脏肿瘤高分辨魔角旋转质子波谱分析
%A DONG Ai-sheng
%A TIAN Jian-ming
%A LU Jian-ping
%A ZUO Chang-jing
%A WANG Li
%A WANG Fei
%A WANG Jian
%A <br>董爱生
%A 田建明
%A 陆建平
%A 左长京
%A 王莉
%A 王飞
%A 汪剑
%J 波谱学杂志
%D 2009
%I 
%X The metabolic profiles in normal human liver tissues(n=9), benign hepatic tumor tissues (n=7) and hepatocellular carcinoma (HCC, n=9) tissues were measured by high-resolution magic angle spinning 1H nuclear magnetic resonance (HR-MAS 1H NMR) spectroscopy. Semi-quantitative analyses showed that the HCC tissues contained significantly higher levels of glycine, taurine, choline, glutamate, alanine, valine and lactate, as compared to the normal and benign liver tissues. The results of this study suggest that the metabolic profiles in the HCC tissues were significantly different from normal liver tissues and benign hepatic tumor tissues, and such differences may be used as references for the diagnosis of HCC.
%K NMR
%K hepatocellular carcinoma
%K HR-MAS 1H NMRS<br>核磁共振(NMR)
%K 肝细胞癌
%K 高分辨魔角旋转质子核磁共振波谱分析
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=6E709DC38FA1D09A4B578DD0906875B5B44D4D294832BB8E&cid=47EA7CFDDEBB28E0&jid=1A3C8C6E452BD1AF5A6B6B99BA3989C9&aid=BBFD4F171B2189754AF07FFCE61BC333&yid=DE12191FBD62783C&vid=96C778EE049EE47D&iid=CA4FD0336C81A37A&sid=987EDA49D8A7A635&eid=11B4E5CC8CDD3201&journal_id=1000-4556&journal_name=波谱学杂志&referenced_num=0&reference_num=23