%0 Journal Article
%T Residual Dipolar Couplings and Their Applications in Determination of Protein Structures<br>残留偶极耦合及其在蛋白质结构研究中的应用
%A LIN Dong-hai
%A LIU Xue-hui
%A <br>林东海
%A 刘雪辉
%J 波谱学杂志
%D 2005
%I 
%X In recent years residual dipolar couplings have been employed to obtain the long-range conformational constraints such as the relative orientations between the chemical bonds in biomolecules for calculation or refinement of three-dimensional structures of proteins and protein complexes in solution This review describes the measurement of residual dipolar couplings using multi-dimensional NMR techniques and their applications in determination of protein structures: refining protein structures, evaluating protein structures, determining the relative orientation between protein domains, obtaining information about ligand conformation and orientation, etc
%K NMR
%K residual dipolar couplings
%K 3D solution structures
%K proteins<br>核磁共振
%K 残留偶极耦合常数
%K 三维溶液结构
%K 蛋白质
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=6E709DC38FA1D09A4B578DD0906875B5B44D4D294832BB8E&cid=47EA7CFDDEBB28E0&jid=1A3C8C6E452BD1AF5A6B6B99BA3989C9&aid=822A0FEDC7304306&yid=2DD7160C83D0ACED&vid=BC12EA701C895178&iid=CA4FD0336C81A37A&sid=CD775AE9DDBD7B53&eid=10F298ED9F164662&journal_id=1000-4556&journal_name=波谱学杂志&referenced_num=0&reference_num=76