%0 Journal Article
%T Succinimide-Linked Nitrone: Synthesis and  ESR Studies<br>链接琥珀酰亚胺的线性硝酮的合成与ESR研究
%J 波谱学杂志
%D 2010
%I 
%X A novel linear nitrone spin-trap, DSC-PBN (N-(4-(((2,5-dioxopyrrolidin-1-yloxy)carbonyloxy)methyl)benzylidene)-2-methylpropan-2-N-oxide), was designed and synthesized. Its structure was characterized by UV, MS and 1H NMR techniques. ESR results showed that the compound could be used to trap various free radicals efficiently, and the ESR spectra of the trapped radicals were readily recognizable. DSC-PBN could easily form a covalent link to the N-terminal peptides (or proteins) via succinimide intermediates, thus showing high potential for biological applications.
%K electron spin resonance (ESR)
%K spin trap
%K nitrone
%K [ free radicals<br>电子自旋共振(ESR)
%K 自由基捕获探针
%K 硝酮
%K 自由基
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=6E709DC38FA1D09A4B578DD0906875B5B44D4D294832BB8E&cid=47EA7CFDDEBB28E0&jid=1A3C8C6E452BD1AF5A6B6B99BA3989C9&aid=FA009A15BFEF33628F4087A90D1FB9C9&yid=140ECF96957D60B2&vid=DB817633AA4F79B9&iid=CA4FD0336C81A37A&sid=E203FB1A272C9DD2&eid=7E8E8B150580E4AB&journal_id=1000-4556&journal_name=波谱学杂志&referenced_num=0&reference_num=24