%0 Journal Article
%T Structure Elucidation of Valacyclovir Hydrochloride by NMR Spectroscopy and Mass Spectroscopy<br>盐酸伐昔洛韦的波谱学研究
%A LIU Li-jun
%A ZHONG Bo-hua
%A MIAO Zhen-chun
%A CHEN Lan-fu
%A <br>刘力军
%A 仲伯华
%A 缪振春
%A 陈兰福
%J 波谱学杂志
%D 2005
%I 
%X Valacyclovir hydrochloride, 2-(2-amino-1, 6-dihydro-6-oxo- 9H-purine-9-yl)methoxy] ethyl-L-valinate hydrochloride, was synthesized from purine through acetylation, hydrolysis, condensation and deprotection reactions. The structure of the target compound was elucidated by combined use of mass spectroscopy and 1D/2D NMR techniques including 1H and 13C NMR, DEPT, 1H-1H COSY, HMQC and HMBC. The 1H and 13C chemical shifts of the compound were completely assigned.
%K NMR
%K MS<br>归属
%K 伐昔洛韦
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=6E709DC38FA1D09A4B578DD0906875B5B44D4D294832BB8E&cid=47EA7CFDDEBB28E0&jid=1A3C8C6E452BD1AF5A6B6B99BA3989C9&aid=D6EBEE757BBC2810&yid=2DD7160C83D0ACED&vid=BC12EA701C895178&iid=38B194292C032A66&sid=F637763636425CAF&eid=AA5FB09E1F81059E&journal_id=1000-4556&journal_name=波谱学杂志&referenced_num=3&reference_num=6