%0 Journal Article
%T Crystal Structure of the N-Benzyloxycarbonyl-alanyl-phenylalanyl-methyl Ester: The Importance of the H-Bonding Pattern
%A Ignacio Alfonso
%A Michael Bolte
%A M. Isabel Burguete
%A Santiago V. Luis
%J Crystals
%D 2011
%I MDPI AG
%R 10.3390/cryst1030163
%X Large crystals of the methyl ester of the N-a-benzyloxycarbonyl protected Ala-Phe dipeptide (Z-AF-OMe) were obtained after the very slow evaporation of a solution of the corresponding carboxylic acid (Z-AF-OH) in methanol containing an excess of HCl. The structure was confirmed by single crystal X-ray diffraction data. It crystallizes in the orthorhombic space group P2 12 12 1 with unit cell dimensions a = 5.0655(6) £¿, b = 8.4614(8) £¿, c = 46.856(5) £¿, V = 2008.3(4) £¿ 3, Z = 4. In the crystal, the molecules form hydrogen bonded chains running along the a axis of the unit cell. Other secondary interactions are also discussed.
%K peptides
%K alanylphenylalanyl derivative
%K crystal structure
%K hydrogen bond
%U http://www.mdpi.com/2073-4352/1/3/163