%0 Journal Article
%T Implication of heparan sulfate proteoglycans in diseases<br>硫酸肝素蛋白多糖在疾病中的作用
%A GONG Feng
%A ZHANG Xiao & LI JinPing
%A Beijing institute of transfusion medicine
%A Beijing
%A China Institute of Complexity Science
%A Qingdao University
%A Qingdao
%A China
%A <br>宫锋
%A 张晓
%A 李晋萍
%J 中国科学 生命科学
%D 2010
%I 
%X Heparan sulfate proteoglycan (HSPG),a group of macromolecular glycoconjugates expressed on the cell surfaces and in the extracellular matrix (ECM),is essential for animal development and homeostasis.HSPG participates in many important biological activities,mostly through interactions of the side heparan sulfate (HS) polysaccharide chains with a wide range of protein ligands.Cell surface HS interacts with growth factors and their receptors,mediating signal transduction.As a main component of the ECM,HSPG mai...
%K 硫酸肝素蛋白多糖
%K 乙酰硫酸肝素
%K 老年性痴呆
%K 肿瘤转移
%K 病毒
%K 炎症
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=DBE4ECF0864647819971514F9C47DC38&aid=515565991C1335023F5617CD5B3E921C&yid=140ECF96957D60B2&vid=1371F55DA51B6E64&iid=38B194292C032A66&sid=3E0812ED84A7B31D&eid=BC084ACE66B62CC8&journal_id=1006-9259&journal_name=中国科学C辑&referenced_num=0&reference_num=0