%0 Journal Article
%T Analyzing the Diversity of Plant Lectins According to Structural Character of Biological Macromolecule<br>从生物大分子结构特征解析植物凝集素的多样性
%A GUO Ming Xiong
%A SUN Gui Hong
%A WU Xian Hui
%A FENG Sheng Yan
%A CHEN Wei Mei
%A AI Jian Yu
%A XIONG Xiao Ran
%A WU Bin
%A <br>郭明雄
%A 孙桂鸿
%A 吴显辉
%A 冯胜彦
%A 陈蔚梅
%A 艾建宇
%A 熊晓然
%A 吴斌
%J 植物科学学报
%D 2003
%I 
%X Mannose specific lectins are widely distributed in higher plants and are believed to play a role in recognition of high mannose type glycans of foreign microorganisms or plant predators. In this paper, we simulated the amino acid residue's structural character of the sugar binding sites of mannose specific binding plant lectins, and calculated and analyzed solvent accessible surface area of the related residue and mean hydrophobicity of the surface patches. Results indicated: (1)Before the plant lectins bind sugar, their conformational variety are consistent; (2)The plant lectins exhibit the structural diversity, which may relate with the diversity of their biological function; (3)During the process of binding sugar, the surface part conformation of the plant lectins can have some variety; this kind of variety may benefit to recognize the plant lectins to the different sugar and bind the differently foreign glycoconjugates, and develop their defense function. To same family plant lectins, although their sequences have high homology, the biological functions have strongly diversity. The structural diversity of mannose specific plant lectins associated with the specific recognition of high mannose type glycans highlights the importance of mannose specific lectins as recognition molecules in higher plants. All results suggest: For biological macromolecule, the function is same, the structure is uncertainly similar; and the structure is similar, the function is uncertainly same.
%K Biological diversity
%K Plant lectins
%K Simulation
%K Accessibility
%K Hydrophobicity<br>生物多样性
%K 植物凝集素
%K 模拟
%K 可及性
%K 硫水性
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=9973DE552EA54506F7AABD4780345ED2&aid=82BE043CD4BAD112&yid=D43C4A19B2EE3C0A&vid=659D3B06EBF534A7&iid=0B39A22176CE99FB&sid=7CE3F1F20DE6B307&eid=F260CE035846B3B8&journal_id=1000-470X&journal_name=武汉植物学研究&referenced_num=2&reference_num=17