%0 Journal Article
%T A novel cell subset: Interferon-producing killer dendritic cells<br>
%A JiongKun Wang
%A FeiYue Xing
%A <br>
%J 中国科学C辑(英文版)
%D 2008
%I Springer
%X Recent reports introduce a novel cell subset of DCs with antigenic phenotypes shared by both NK cells and B cells, but without surface markers of pDCs and T cells, appearing to be a chimera of NK cells and DCs, namely interferon-producing killer dendritic cells(IKDCs).IKDCs not only secret type I and type II interferons to recognize and kill tumor cells effectively, but also express MHC-II molecules to present antigens.Thus, IKDCs are considered as important immunosurveilance cells for tumors, providing a link between innate and adaptive immunity.
%K IKDCs
%K cDCs
%K pDCs
%K NK cells<br>
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=180CF3A72E750F3261A8A60EDC957784&aid=AB35E62A3A81A582E73B095955ABF29E&yid=67289AFF6305E306&vid=987EDA49D8A7A635&iid=5D311CA918CA9A03&sid=93661EC4C0CCEA67&eid=DEE640F0CDC9D495&journal_id=1674-7305&journal_name=ScienceChina.Lifesciences&referenced_num=0&reference_num=26