%0 Journal Article
%T Immunomodulatory effects of Caulerpa racemosa var peltata polysaccharide and its selenizing product on T lymphocytes and NK cells in mice<br>
%A SHEN WeiZai
%A WANG Hui
%A GUO GuoQing &
%A TUO JingJing
%A <br>
%J 中国科学C辑(英文版)
%D 2008
%I Springer
%X A polysaccharide, CrvpPS, was isolated from Caulerpa racemosa var peltata. It was reacted with nano-selenium in distilled water containing ascorbic acid (Vit C) to form a stable CrvpPS-nano-Se complex. The immunomodulatory effects of CrvpPS and CrvpPS-nano-Se on T lymphocytes subgroups and NK cells in mice were investigated. After intragastric administration for 10 days separately, both CrvpPS and CrvpPS-nano-Se showed significant stimulatory functions to thymus gland of mice. Moreover, the CrvpPS-nano-Se induced the percentage of CD3 , CD3 CD4 , NK cells and the CD4 /CD8 value to increase significantly (P<0.05) when analyzed by flow cytometry, which is better than the CrvpPS, sucrose-nano-Se, and even the positive drug levamisole.
%K Caulerpa racemosa var peltata polysaccharides (CrvpPS)
%K nano-Se
%K T lymphocyte subgroups
%K natural killer cells
%K immunomodulation
%K flow cytometric analysis<br>
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=180CF3A72E750F3261A8A60EDC957784&aid=642976D094CB08CF925F2733AEFF4DB7&yid=67289AFF6305E306&vid=987EDA49D8A7A635&iid=9CF7A0430CBB2DFD&sid=FC6FCA5A7559F1FB&eid=0018E43E61963A72&journal_id=1674-7305&journal_name=ScienceChina.Lifesciences&referenced_num=0&reference_num=18