%0 Journal Article
%T Latency represents sound frequency in mouse IC
%A Qiang Qiu
%A Jie Tang
%A ZuLin Yu
%A Juan Zhang
%A YingJie Zhou
%A ZhongJu Xiao
%A JunXian Shen
%A <br>
%J 中国科学C辑(英文版)
%D 2007
%I Springer
%X Frequency is one of the fundamental parameters of sound.The frequency of an acoustic stimulus can be represented by a neural response such as spike rate,and/or first spike latency(FSL)of a given neuron.The spike rates/frequency function of most neurons changes with different acoustic ampli-tudes,whereas FSL/frequency function is highly stable.This implies that FSL might represent the fre-quency of a sound stimulus more efficiently than spike rate.This study involved representations of acoustic frequency by spike rate and FSL of central inferior colliculus(IC)neurons responding to free-field pure-tone stimuli.We found that the FSLs of neurons responding to characteristic frequency(CF)of sound stimulus were usually the shortest,regardless of sound intensity,and that spike rates of most neurons showed a variety of function according to sound frequency,especially at high intensities.These results strongly suggest that FSL of auditory IC neurons can represent sound frequency more precisely than spike rate.
%K first spike latency
%K characteristic frequency
%K representation
%K inferior colliculus
%K mouse<br>
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=180CF3A72E750F3261A8A60EDC957784&aid=1D63963F2C7347E08A8F079C48CCBD7D&yid=A732AF04DDA03BB3&vid=771152D1ADC1C0EB&iid=0B39A22176CE99FB&sid=B799C1769FCACDC8&eid=7ABC4505E3960D2B&journal_id=1674-7305&journal_name=ScienceChina.Lifesciences&referenced_num=0&reference_num=29