%0 Journal Article
%T Mechanism of Nicotine N-demethylation to Nornicotine in Tobacco<br>烟草去甲基尼古丁产生的机理
%A Baiyi An
%A Jinghui Xi
%A Shuo Yang
%A Dongyun Hao
%A <br>安佰义
%A 席景会
%A 杨朔
%A 郝东云
%J 植物学报
%D 2007
%I 
%X Nornicotine is produced by the N-demethylation of nicotine during the post-harvest treatment of tobacco leaves.Nornicotine in tobacco serves as the precursor in synthesis of the well-characterized carcinogen N'-nitrosonornicotine (NNN), one of the tobacco-specific nitrosamines (TSNAs), and consequently damages the health of tobacco smokers and passive smokers. Studies of the mechanism of nicotine N-demethylation have, over the last decades, attracted serious attention because of its importance in plant physiological research and commerce. In this review, we discuss the history and mechanisms of nicotine Ndemethylation and the factors that affect this enzymatic reaction. The current advances in nicotine N-demethylation in tobacco provide important insights into improving the quality of tobacco and developing hazard-reduced tobacco products.
%K <br>去甲基化
%K 尼古丁
%K 尼古丁去甲基化酶
%K 去甲基尼古丁
%K 烟草
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=97AE3D0EBF25E42C466FEF50E492F710&aid=E00EDD65E4BD40E048E3686A2BCFA9B0&yid=A732AF04DDA03BB3&vid=B91E8C6D6FE990DB&iid=E158A972A605785F&sid=B34BDD6A690A04C0&eid=385E3C2062167B88&journal_id=1674-3466&journal_name=植物学报&referenced_num=0&reference_num=40