%0 Journal Article
%T Composition and Distribution of Pseudogenes and Their Molecular Evolution<br>假基因的组成、分布及其分子进化
%A Zhihua Huang
%A Qingzhong Xue
%A <br>黄志华
%A 薛庆中
%J 植物学报
%D 2006
%I 
%X Pseudogenes are sequences of genomic DNA with such similarity to functional genes that they are regarded as nonfunctional copies or close relatives of genes. Homology search of genomic DNA can reveal pseudogene sequences, and some properties of pseudogenes such as population, distribution, and homology family can be examined. Pseudogenes are important resources in evolutionary and comparative genomics and are considered gene fossils, because they provide molecular records of the ancient genes that existed in the genome millions of years ago. Comparison of genes and pseudogenes offers new insights into the evolutionary history of genes and the stability of the genome as a whole, for example, the determination of the natural selection pressure of pseudogenes with Ka/Ks, the relation and the evolutionary distance between species and tendency of pseudogenes and the origin of DNA mutation.
%K <br>假基因
%K 基因组
%K 进化
%K 生物信息学
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=97AE3D0EBF25E42C466FEF50E492F710&aid=77648B3112E5C755688885CA4E51A0C0&yid=37904DC365DD7266&vid=EA389574707BDED3&iid=E158A972A605785F&sid=EE23223CE4332BD7&eid=A53D7AA35F9929AF&journal_id=1674-3466&journal_name=植物学报&referenced_num=0&reference_num=23