%0 Journal Article
%T Research advances in ecotoxicology and risk assessment of chemical mixtures at low doses<br>低剂量混合污染生态毒理与风险评价研究进展
%A LI Xinxin
%A SONG Yufang
%A ZHANG Wei
%A YANG Daoli
%A ZHOU Qixing
%A SUN Tieheng
%A <br>李昕馨
%A 宋玉芳
%A 张薇
%A 杨道丽
%A 周启星
%A 孙铁珩
%J 应用生态学报
%D 2006
%I 
%X Chemicals in the environment often exist as mixtures and at low doses, whose ecotoxicological diagnosis and risk assessment are hard to be done with the help of the research results on the ecotoxicity of high-level exposure of single chemicals. This paper reviewed the research advances in ecotoxicology and risk assessment of low-dose chemical mixture contamination, with the focus on the molecular toxicological methods and the risk assessment approaches and schemes of simple and complex mixtures. Comments were given on the development directions of low-dose chemical mixture research, including the necessity of searching for sensitive endpoints, involving the approaches of other disciplines, increasing data accumulation, and setting up a comprehensive and identical risk assessment system.
%K Chemical mixture
%K Low dose
%K Molecular toxicology
%K Risk assessment<br>化学混合物
%K 低剂量
%K 分子毒理学
%K 风险评价
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=42FEDDFE54F8BCD9D5FD1926ABDD7722&aid=CCE202AB0DC89D82&yid=37904DC365DD7266&vid=BCA2697F357F2001&iid=DF92D298D3FF1E6E&sid=3EF235AF78C45721&eid=DF8B97D5075E2D12&journal_id=1001-9332&journal_name=应用生态学报&referenced_num=2&reference_num=53