%0 Journal Article
%T Halophilous microbial groups in saline lake of Qinghai and the growth characteristics and anti-microbial and anti-tumor activities of F16.<br>青海盐湖嗜盐微生物类群及F16菌株生长特性和抗菌、抗肿瘤活性
%A YE Yangfang
%A YAN Xiaojun
%A HUANG Xiaochun
%A CHEN Ye
%A CHEN Haimin
%A ZHU Shihua
%A <br>叶央芳
%A 严小军
%A 黄晓春
%A 陈烨
%A 陈海敏
%A 朱世华
%J 应用生态学报
%D 2006
%I 
%X A total of forty-five halophilous microorganisms were isolated from the sediment of saline lake in Qinghai Province, among which, filamentous fungus F16 showed the highest activity of anti-microorganism and anti-tumor. The ethyl acetate extract of F16 culture filtrate showed a strong cytotoxicity, and could inhibit the growth of four kinds of bacteria, especially Escherichia coli. When the concentration of the crude extract was 50 microg x ml(-1), the inhibition rate to liver cancer cell BEL7402 reached 76. 91%. The optimal temperature for F16 growth was 15 degrees C , and the increase of salt concentration in media would inhibit its growth. When the concentration of salt surpassed 15% , F16 could not survive. F16 grew well when the pH value ranged from 5 to 9.
%K Halophilous microorganism
%K Anti-microorganism
%K Anti-tumor
%K Saline lake<br>嗜盐微生物
%K 抗菌
%K 抗肿瘤
%K 盐湖
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=42FEDDFE54F8BCD9D5FD1926ABDD7722&aid=C3E90AB9BD66BC0E&yid=37904DC365DD7266&vid=BCA2697F357F2001&iid=F3090AE9B60B7ED1&sid=8A15F8B0AA0E5323&eid=8CAA3A429E3EA654&journal_id=1001-9332&journal_name=应用生态学报&referenced_num=3&reference_num=22