%0 Journal Article
%T Association between mitochondrial DNA mutations and cancer in human
人类线粒体DNA突变与癌症
%A ZHANG Shu-Ping
%A SONG Shu-Juan
%A LI Ya-Xuan
%A
张淑萍
%A 宋书娟
%A 李雅轩
%J 遗传
%D 2008
%I
%X Mitochondria are essential organelles that generate cellular energy in cells. Mutations of mitochondrial DNA (mtDNA) have been identified in various types of cancer, suggesting a complex relationship between mtDNA and cancer. This review focuses on the possible correlation between the mtDNA mutation and cancer. Additionally, possible causes for mtDNA mutations and applications for detecting mtDNA mutations in cancer are discussed.
%K 线粒体DNA
%K 癌细胞
%K 突变
%K 检测
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=3E23F50E071DF18E21B2F5AEE4F1FA5E&aid=41384B5AC25293FB1D16CCD7C8F418CB&yid=67289AFF6305E306&vid=340AC2BF8E7AB4FD&iid=38B194292C032A66&sid=96A53C367B5173D7&eid=DC330B09A33F1455&journal_id=0253-9772&journal_name=遗传&referenced_num=2&reference_num=24