%0 Journal Article
%T Use of PCR Related Methods in Detection of Gene Mutation<br>PCR及其衍生技术在基因突变检测中的应用 Use of PCR Related Methods in Detection of Gene Mutation
%A Zhi-Qiang Yan
%A Sheng-Li Yang
%A Yi Gong
%A <br>颜志强
%A 杨胜利
%A 龚毅YAN Zhi-Qiang
%A YANG Sheng-Li
%A GONG Yi
%J 遗传
%D 2003
%I 
%X Many inherited diseases and drug resistance have been attributed to mutations in corresponding genes. In this paper, several techniques based on PCR used in diagnosis were concluded. The development and research progress of Mismatch PCR were discussed in details. Some information about an assay that we developed for detection of antimicrobial resistance to quinolones was also described.
%K inherited diseases
%K drug resistance
%K gene mutation
%K mismatch PCR<br>遗传性疾病
%K 抗药性
%K 基因突变
%K 错配PCR
%K 突变检测
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=3E23F50E071DF18E21B2F5AEE4F1FA5E&aid=EDF14E5B3989E9C4&yid=D43C4A19B2EE3C0A&vid=C5154311167311FE&iid=0B39A22176CE99FB&sid=FEF02B4635FE8227&eid=1E41DF9426604740&journal_id=0253-9772&journal_name=遗传&referenced_num=4&reference_num=11