%0 Journal Article %T Genetic Polymorphism of FIBRA,DHFRP2 and ACTBP2 and Their Forensic Application in Yunnan Han Population
云南汉族群体FIBRA、DHFRP2、ACTBP2基因座多态性及其法医学应用 %A JING Qiang %A NIE Sheng-jie %A
景强 %A 聂胜洁 %J 遗传 %D 2002 %I %X To investigate the genetic polymorphism of FIBRA,DHFRP2 and ACTBP2 in Yunnan Han population as well as their application in forensic science, EDTA-blood specimens were collected from 200 healthy individuals. The DNA were extracted either by the Chloro form, phenol method or by the Chelex-100 method. The PCR products were analyzed by PAG vertical electrophoresis, following by silver staining. All gene frequencies, discrimination power (DP) ,exclusion of paternity probability (EPP) ,heterozygosity (H) ,polymorphisms information content (PIC) ,matching probability (PM) as well as the Hardy-Weinberg test were calculated. The obtained data are beneficial in the understanding of population genetics of the three STR loci in Yunnan Han population and the results suggest that these loci are valuable genetic markers for paternity testing and personal identification in forensic science practice. %K short tandem repeat %K Amp-FLP %K genetic polymorphism
云南汉族群体 %K FIBRA %K DHFRP2 %K ACTBP2 %K 基因座 %K 短串联重复序列 %K 扩增片段长度多态性 %K 遗传多态性 %U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=3E23F50E071DF18E21B2F5AEE4F1FA5E&aid=8559E5FC56E70014&yid=C3ACC247184A22C1&vid=B91E8C6D6FE990DB&iid=94C357A881DFC066&sid=F3549E0657848E2A&eid=20ADD38F841C6A4B&journal_id=0253-9772&journal_name=遗传&referenced_num=0&reference_num=10