%0 Journal Article
%T Effects of MTNR1A gene on litter size in a Large White and a Landrace Herd<br>MTNR1A基因对大白猪和长白猪产仔数的影响
%A WANG Xiao-Feng
%A WANG Ai-Guo
%A FU Jin-Lian
%A LI Zong-Jin
%A HAN Li-Ping
%A YANG Shu-Ming
%A <br>王晓凤
%A 王爱国
%A 傅金恋
%A 李宗进
%A 杨淑明
%A 韩丽萍
%J 遗传
%D 2006
%I 
%X Two pairs of primers were designed based on the known sequence in GenBank for amplification of MTNR1A gene in a Large White and a Landrace herd. Using PCR-SSCP (single strand conformation polymorphism), we found a single nucleotide polymorphism(SNP) within the product amplified from the first pair of primers. PCR products from randomly selected different genotypes were sequenced after were recovered and purified. Results revealed a synonymous single base mutation(G-->A) at +159bp(sequence numbering based on Genbank accession number U73326) for the BB genotype. When analyzed for association with litter size traits, this MTNR1A SNP was found to have no significant effect on litter size traits.
%K MTNR1A<br>猪
%K 产仔数
%K 单核苷酸多态性
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=3E23F50E071DF18E21B2F5AEE4F1FA5E&aid=1E84DD17727A67FF&yid=37904DC365DD7266&vid=D3E34374A0D77D7F&iid=DF92D298D3FF1E6E&sid=8C8D39B86A1EED4F&eid=AF407E3178C0B145&journal_id=0253-9772&journal_name=遗传&referenced_num=1&reference_num=9