%0 Journal Article
%T The Relationship of DNA Methylation and Histone Methylation<br>DNA甲基化与组蛋白甲基化的关系
%A LI Jan-Xu
%A LIU Hong-Lin
%A <br>李建许
%A 刘红林
%J 遗传
%D 2004
%I 
%X In and out of the eukaryotic genomes, there exist many covalent modifications, of which are the methylation of DNA and histones, and they are both involved in genes silencing, in which the methylation of DNA and H3K9 are synergistic, but the methylation of H3K4 is antagonistic to them.The rencent studies show that these two methylations are correlated, that is, DNA methylation is dependent on the methylation of H3K9. However, the relationship of these two methylations is more complicated in mammals than in lower eukaryotons and plants.
%K DNA<br>组蛋白
%K 甲基化
%K 甲基转移酶
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=3E23F50E071DF18E21B2F5AEE4F1FA5E&aid=94825BD11E614639&yid=D0E58B75BFD8E51C&vid=96C778EE049EE47D&iid=0B39A22176CE99FB&sid=866F8A6B640835A7&eid=B7BFA4B351E4C682&journal_id=0253-9772&journal_name=遗传&referenced_num=1&reference_num=30