%0 Journal Article
%T Research Progress and Prospect of Animal Gene Targeting<br>动物基因敲除研究的现状与展望
%A Xiang-Ping Li
%A Wei-Zhuo Xu
%A Ning Li
%A <br>李湘萍
%A 徐慰倬
%A 李宁
%J 遗传
%D 2003
%I 
%X Established upon the embryo stem cell technique and homologous recombination, gene targeting has been widely used in the genome specific manipulation, especially applied in the genetic trait modification of transgenic animal. Our paper reviewed the history of transgenic animal, somatic cloning and gene targeting, which indicates the influence towards the current status and prospect of the transgenic animal production.
%K transgene
%K cloning
%K gene targeting<br>转基因
%K 克隆
%K 基因打靶
%K 研究现状
%K 动物
%K 基因敲除
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=3E23F50E071DF18E21B2F5AEE4F1FA5E&aid=6A961C020A762AB6&yid=D43C4A19B2EE3C0A&vid=C5154311167311FE&iid=CA4FD0336C81A37A&sid=35FC3610259C2B32&eid=7E8E8B150580E4AB&journal_id=0253-9772&journal_name=遗传&referenced_num=13&reference_num=59