%0 Journal Article
%T Genetic Polymorphism of 23 Y Chromosome Biallelic Markers in Chinese Han Population<br>汉族群体23个Y染色体双等位基因标记遗传多态性研究
%A HUANG Dai-Xin
%A YANG Qing-En
%A Yin Hui
%A ZHAI Xian-Dun
%A YANG Rong-Zhi
%A <br>黄代新
%A 杨庆恩
%A 尹 慧
%A 翟仙敦
%A 杨荣芝
%J 遗传
%D 2006
%I 
%X To search polymorphic Y chromosome biallelic markers in Chinese Han population, and obtain their population genetic data. Genotyping of 23 biallelic markers on human Y chromosome (M7, M9, M50, M88, M89, M95, M111, M117, M119, M121, M122, M134, M159, M164, M175, M214, LINE1, MSY2, RPS4Y711, SRY465, IMS-JST164520, IMS-JST021354 and IMS-JST003305) were carried out in a sample of 160 unrelated Chinese male individuals living in Wuhan using fragment length discrepant allele specific PCR (FLDAS-PCR) and PAGE technique. In all 23 biallelic markers, genetic polymorphism were identified for 20 loci in Wuhan Han population except for M50, M159 and M164, and the ranges of gene diversity (GD) were 0.0126-0.4855. A total of 35 different haplogroups (Hg1-35) were observed and the haplogroup diversity (HD) was 0.9471. The haplogroups formed by 20 biallelic markers are highly polymorphic, and can be used in forensic science and population evolution studies.
%K Y chromosome
%K biallelic marker
%K genetic polymorphism
%K haplogroup<br>Y染色体
%K 双等位基因标记
%K 遗传多态性
%K 单体群
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=3E23F50E071DF18E21B2F5AEE4F1FA5E&aid=109623E44E491BC1&yid=37904DC365DD7266&vid=D3E34374A0D77D7F&iid=DF92D298D3FF1E6E&sid=4198A31627C9B2A6&eid=B3645A659773B73C&journal_id=0253-9772&journal_name=遗传&referenced_num=0&reference_num=12