%0 Journal Article
%T The Expression of Pseudogene HMGA1L2 in Thyroid Lesions<br>假基因HMGA1L2在甲状腺肿瘤中的表达
%A WANG Guo-Liang
%A ZHANG Guo-Chang
%A LI Feng
%A ZHAO Jin
%A HU Wen-Hao
%A ZHANG Jin-Fang
%A YIN Xiang-Li
%A GUO Chang-Jun
%A JIANG Jin-Fang
%A LIANG Wei-Hua
%A <br>王国亮
%A 张国昌
%A 李 锋
%A 赵 瑾
%A 胡文浩
%A 张金芳
%A 尹香利
%A 郭长军
%A 蒋金芳
%A 梁伟华
%J 遗传
%D 2006
%I 
%X Pseudogene HMGA1L2 mRNA level was detected using RT-PCR in 50 cases of thyroid lesions. The results show that HMGA1L2 mRNA was found in all 12 cases of nodular goiter, all 9 cases of thyroid adenoma and all 15 cases of papillary carcinoma. In 14cases of thyroid follicular carcinoma, However, the frequence of HMGA1L2 mRNA expression was 35.7%, which was significantly different from that in other types of thyroid lesions (P<0.05). This is the first report of mRNA expression of pseudogene HMGA1L2 in nodular goiter and thyroid tumors. It indicate that pseudogene HMGA1L2 expression analysis could be helpful in differentiation between follicular carcinoma and adenoma.
%K HMGA1L2
%K RT-PCR<br>假基因
%K 甲状腺肿
%K 甲状腺肿瘤
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=3E23F50E071DF18E21B2F5AEE4F1FA5E&aid=315CE773139F620F&yid=37904DC365DD7266&vid=D3E34374A0D77D7F&iid=708DD6B15D2464E8&sid=995E04834DE9F169&eid=CDE3E49FCD9EE463&journal_id=0253-9772&journal_name=遗传&referenced_num=0&reference_num=17