%0 Journal Article
%T HLA-DM polymorphisms in Guizhou Han individuals<br>贵州汉族人群HLA-DM基因多态性分析
%A JIANG Hong-Mei
%A WANG Yong-Xia
%A WANG Yong
%A <br>蒋红梅
%A 王永霞
%A 王勇
%J 遗传
%D 2008
%I 
%X Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) was used to determine genetic polymorphisms at HLA-DMA/DMB loci in 125 healthy unrelated Han individuals from Guizhou Province. We found that the frequencies of DMA*0101, DMA*0102, and DMA*0103 alleles were 0.720, 0.242, and 0.036, respectively. The fre-quencies of DMB*0101, DMB*0102, DMB*0103, and DMB*0104 alleles were 0.620, 0.156, 0.188, and 0.036, respec-tively. Common genotypes for DMA were DMA*0101/0101 and 0101/0102. Common genotypes for DMB were DMB*0101/0101, 0101/0102, and 0101/0103. These results showed that the genetic polymorphism of HLA-DM gene in Han individuals from Guizhou Province is distinct from other regions.
%K HLA-DM<br>基因多态性
%K 汉族人群
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=3E23F50E071DF18E21B2F5AEE4F1FA5E&aid=6B34E0B479DD8E4CD20B95088A3395CD&yid=67289AFF6305E306&vid=340AC2BF8E7AB4FD&iid=9CF7A0430CBB2DFD&sid=09D7E2FA8227CA7B&eid=59B00AA7F83CF649&journal_id=0253-9772&journal_name=遗传&referenced_num=0&reference_num=11