%0 Journal Article
%T Detection and Analysis of the Sub-types of -α3. 7 in Chinese<br>中国人α珠蛋白基因-α3.7缺失亚型的研究 Detection and Analysis of the Sub-types of -α3.7 in Chinese
%A Su-Qin Chen
%A Hong-Yi Li
%A Zheng Chen
%A Shan Duan
%A Lu-Ming Chen
%A Qiu-Hong Tian
%A Chuan-Shu Du
%A <br>陈素琴
%A 李洪义
%A 陈争
%A 段山
%A 陈路明
%A 田秋红
%A 杜传书CHEN Su-Qin
%A LI Hong-Yi
%A CHEN Zheng
%A DUAN Shan
%A CHEN Lu-Ming
%A TIAN Qiu-Hong
%A DU Chuan-Shu
%J 遗传
%D 2003
%I 
%X -alpha3.7 is a common deletional alpha-thalassemia-2 in China. According to different recombination sites,-alpha3.7 can be divided into -alpha3.7I,-alpha3.7IIand -alpha3.7III. The frequency and population distribution of these -alpha3.7 are quite different. In this study,we detected 56 patients among Chinese population of -alpha3.7 defect in alpha globin gene by PCR method, then the PCR product was digested by the restriction enzyme ApalI and BalI. The sub-typing result shows that in the 56 cases of -alpha3.7 defect,54 out of 56 is -alpha3.7I,2 out of 56 is -alpha3.7II and none of -alpha3.7III is detected. This result enriches the data about the alpha thalassemia genotypes of Chinese people.
%K 中国人
%K α珠蛋白基因
%K 缺失亚型
%K α地中海贫血
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=3E23F50E071DF18E21B2F5AEE4F1FA5E&aid=0BD470A1E379FC89&yid=D43C4A19B2EE3C0A&vid=C5154311167311FE&iid=B31275AF3241DB2D&sid=95F0D0DE8CD6F434&eid=7004BE6E41AAF52C&journal_id=0253-9772&journal_name=遗传&referenced_num=0&reference_num=18