%0 Journal Article
%T DNA methyltransferases: the role in regulation of gene expression and biological processes<br>DNA甲基转移酶的表达调控及主要生物学功能
%A 苏玉
%A 王溪
%A 朱卫国
%J 遗传
%D 2009
%I 
%X Both hitone modification and DNA methylation remodulate chromatin structure and control gene expression or silence. As a main enzyme for DNA methylation, DNA methyltransferase (Dnmt) is not only associated with DNA methylation, but also links to many important biological activities, including cell proliferation, senescence and cancer development. This review focuses on structure, regulation and function in biological processes of Dnmt.
%K DNA甲基转移酶
%K DNA甲基化
%K 表观遗传学
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=3E23F50E071DF18E21B2F5AEE4F1FA5E&aid=2274EFDD168F7C25444E3A854EB3AD7F&yid=DE12191FBD62783C&vid=4AD960B5AD2D111A&iid=708DD6B15D2464E8&sid=DE3C727FE2D9509D&eid=8DEAC935CD342902&journal_id=0253-9772&journal_name=遗传&referenced_num=3&reference_num=52