%0 Journal Article %T 基于生物信息学的SNP候选位点搜寻方法 Discovery of Candidate SNP by Bioinformatic Methods %A 陈炜 %A 张戈 %A 张思仲CHEN Wei %A ZHANG Ge %A ZHANG Si-zhong %J 遗传 %D 2001 %I %X 单核苷酸多态性(Single Nucleotide Polymorphism,SNP)是人类基因组中最常见的遗传多态,在遗传学研究的很多方面具有重要的作用。它的搜寻正受到广泛关注。近年来,国际上出现了一种基于生物信息学的发掘SNP新方法。本文对该方法的两种策略及其各自所存在的问题作一介绍。 Abstract:Single Nucleotide Polymorphism (SNP), the most common form of human genetic variation, represents a valuable resources for a variety of genetic research. There is considerable interest in the discovery of it. Recently, a new method based on bioinfomatics has been developed for the discovery of SNP. In this paper, the two strategy of this method and their respective problem are discussed. %K 单核苷酸多态性(Single %K Nucleotide %K Polymorphism %K SNP) %K 生物信息学 %K Keywords %K Single %K Nucleotide %K Polymorphism %K (SNP) %K bioinformatics %U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=3E23F50E071DF18E21B2F5AEE4F1FA5E&aid=4039D7B072F6514C5B51781084C4348C&yid=14E7EF987E4155E6&vid=EA389574707BDED3&iid=0B39A22176CE99FB&sid=D59111839E7C8BDF&eid=5B5B75F4854B8331&journal_id=0253-9772&journal_name=遗传&referenced_num=0&reference_num=0