%0 Journal Article %T A Study of the Distribution about Genotype and Allele Frequencies of T102C Polymorphism in the 5-HT2a Receptor Gene in Chinese Han Population in Shanghai
上海地区汉族人5-HT2a受体基因T102C多态性的基因频率分布 A Study of the Distribution about Genotype and AlleleFrequencies of T102C Polymorphism in the 5-HT2a Receptor Gene inChinese Han Population in Shanghai %A LUO Xingguang %A JIANG Sanduo %A JIANG Kaida %A GU Niufan %A LIN Sicui %A QIAN Yiping %A
罗星光 %A 江三多 %A 江开达 %A 顾牛范 %A 林嗣萃 %A 钱伊萍LUO Xing-guang %A JIANG San-duo %A JIANG Kai-da %A GU Niu-fan %A LIN Si-cui %A QIAN Yi-ping %J 遗传 %D 1998 %I %X To investigate the distribution about genotype and allele frequencies of T102C polymorphism in the 5-HT2a receptor gene in Chinese Han population, the genotypes and alleles of 226 healthy person were examined with Restriction Fragment Length Polymorphisms(RFLPs) technique The genotype frequencies are as follows: A1/A2=0 5044,A1/A1=0 2965,A2/A2=0 1991,respectively, and the allele frequencies are as follows: A1=0 5487,A2=0 4513, respectively The heterozygosity(H) is 0 5044, the expected heterozygosity(h) is 0 4953, and the Polymorphism Information Content(PIC) is 0 3726 Our findings suggest that the T102C polymorphism in 5-HT2a receptor gene may have suitable information to be used for association study or forensic identification %K HT2a receptor gene %K T102Cpolymorphism %K Chinese Han population
中国汉族人,5-HT2a受体基因,T102C多态性 %U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=3E23F50E071DF18E21B2F5AEE4F1FA5E&aid=149FADE2E90672B5DB51364D0D37F4BC&yid=8CAA3A429E3EA654&vid=A04140E723CB732E&iid=94C357A881DFC066&sid=C5154311167311FE&eid=DB817633AA4F79B9&journal_id=0253-9772&journal_name=遗传&referenced_num=5&reference_num=4