%0 Journal Article
%T Effect of Anticancer Drugs on Nuclear Damage in Lymphocytes and Germ Cells of Periplaneta fulginosa<br>抗癌药对黑胸大蠊淋巴细胞和生殖细胞核结构的损伤 Effect of Anticancer Drugs on Nuclear Damage in Lymphocytes and Germ Cells of Periplaneta fulginosa
%A Dai Xiaohuang
%A Huang Yue
%A <br>戴晓煌
%A 黄跃DAI Xiao-Huang
%A HUANG Yue
%J 遗传
%D 1996
%I 
%X 0.1%, 0.3%, 0.5%Thio-TEPA induced 6.3%, 10.5% and 14.2% chromosome break or gap in spermatocyte of coockroach respectively. This was markedly higher than those in oocyte. In doses from 0.1 to 0.5 Tho-TEPA the frequency of micronucleus increased parallely with nuclear damage.0.1 %, 0.3%,0.5% 5-fluorouracil induced 3.5%, 9.8%, 16.2% chromosome break or gap in oocytes respectively. This was paralled with the frequency of micronllcleus in lymphocytes of the female. 5-fluorouracil showed not marked effect on spermatocyte.
%K Micronucleus
%K Chromosome break or gap<br>微核
%K 染色体断裂
%K 裂隙
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=3E23F50E071DF18E21B2F5AEE4F1FA5E&aid=2F3F9D1C0B064B8D4FBFB743C7B3CB3C&yid=8A15F8B0AA0E5323&vid=13553B2D12F347E8&iid=38B194292C032A66&sid=BC12EA701C895178&eid=B91E8C6D6FE990DB&journal_id=0253-9772&journal_name=遗传&referenced_num=0&reference_num=1