%0 Journal Article
%T MODULATION OF THE PRIMARY HUMORAL IMMUNITY BY EMOTIONAL STRESS<br>电击信号应激对大鼠体液免疫及内分泌功能的影响
%A Shao Feng
%A Lin Wenjuan
%A Wang Weiwen
%A Zheng Li
%A <br>邵枫
%A 林文娟
%A 王玮雯
%A 郑丽
%J 心理学报
%D 2000
%I 
%X The emotional stress induced by footshock apparatus as signal stimuli was investigated for its effect on the primary humoral immunity and endocrine response of rats. The reactivity of primary humoral immunity was tested by determing the value of specific IgG antibody after immunization with OVA, and the value of catecholamine and corticosterone were used to measure the endocrine response. Our results showed that ten minutes per day, six days uncontrolled footshocks could not decrease significantly the primary humoral immune response of rats, but footshocks and emotional stress together could decrease the anti-OVA IgG antibody production and spleen index significantly. At the same time, emotional stress could increase the levels of catecholamine and corticosterone significantly. It was concluded that immune and endocrine system were capable of reacting specifically to psychological stimuli.
%K emotional stress
%K primary humoral immunity
%K catecholamine
%K corticosterone<br>情绪应激
%K 原发性体液免疫反应
%K 儿茶酚胺
%K 皮质酮.
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=C94E3F05CFD5644C9DAA97BEB9148D4784B6B22E64D84F4E&jid=1EE72F392B87F45015B3CA6D9A7AFA6F&aid=0541BB48FF3AB9FD&yid=9806D0D4EAA9BED3&vid=9971A5E270697F23&iid=E158A972A605785F&sid=B7ACE2F11789CAE0&eid=4BEA9A781F286FC6&journal_id=0439-755X&journal_name=心理学报&referenced_num=19&reference_num=13