%0 Journal Article
%T Investigation of bubble dynamics in ultrasonic sonoporation<br>超声波声孔效应中气泡动力学的研究
%A Chen Qian
%A Zou Xin-Ye
%A Cheng Jian-Chun
%A <br>陈谦
%A 邹欣晔
%A 程建春
%J 物理学报
%D 2006
%I 
%X During the process of quickly producing pathologic sections of the living tissues with ultrasonic sonoporation, it has been found that the exciting ultrasonic signal has an evident effect on the pathologic section. For the sake of understanding the effect and obtaining the best state of quickly producing pathologic section, the bubble dynamics in ultrasonic sonoporation is investigated by constructing a model of cavitated bubbles and altering the parameters, such as the ultrasonic signal frequency, acoustic pressure, bubbles' original radius and viscosity of the fluid. Numerical simulations indicate that radial vibration of cavitating bubble can keep on a steady process of expanding, shrinking, and vibrating in a given rang of frequencies, and one can find out the best original radius for obtaining the maximal cavitation. There exist a best cavitation regions which are determined by the parameters, i.e., the ultrasonic signal frequency, acoustic pressure, bubbles' original radius and viscosity of body fluid.
%K sonoporation
%K ultrasonic cavitate
%K bubble vibration
%K stable cavitation area<br>声孔效应
%K 超声空化
%K 气泡振动
%K 稳态空化域
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=6E709DC38FA1D09A4B578DD0906875B5B44D4D294832BB8E&cid=47EA7CFDDEBB28E0&jid=29DF2CB55EF687E7EFA80DFD4B978260&aid=E6524425F53A62ED&yid=37904DC365DD7266&vid=E514EE58E0E50ECF&iid=59906B3B2830C2C5&sid=C3C06BCDE690E911&eid=624532E7BE52A38B&journal_id=1000-3290&journal_name=物理学报&referenced_num=6&reference_num=10